China Factory Outlets Sagent Heparin - Pepsin of Deebio for Treating Dyspepsia Caused by Over Taking Proteinic Foods – Deebiotech factory and manufacturers

Factory Outlets Sagent Heparin - Pepsin of Deebio for Treating Dyspepsia Caused by Over Taking Proteinic Foods – Deebiotech

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Factory Outlets Sagent Heparin - Pepsin of Deebio for Treating Dyspepsia Caused by Over Taking Proteinic Foods – Deebiotech Detail:

Detail

1. Characters: White or slightly yellow, crystalline or amorphous powder.

2. Extraction Source: Porcine gastric mucosa.

3. Process: Pepsin is isolated from the pig’s gastric mucosa using a unique extraction technique.

4. Indications and uses: It is widely used for the dyspepsia caused by over taking proteinic foods, digestive hypofunction in the recovering period and lack of stomach proteinase caused by chronic atrophic gastritis, gastric cancer and malignant anaemia.Pepsin is an enzyme that is secreted in the digestive track of mammals. It works to break down proteins into smaller peptides which can readily be absorbed by the small intestine.

5. Biochem/physiol Actions: Unlike many other peptidases, pepsin hydrolyzes only peptide bonds, not amide or ester linkages. The cleavage specificity includes peptides with an aromatic acid on either side of the peptide bond, especially if the other residue is also an aromatic or a dicarboxylic amino acid. Increased susceptibility to hydrolysis occurs if there is a sulfur-containing amino acid close to the peptide bond, which has an aromatic amino acid. Pepsin will also preferentially cleave at the carboxyl side of phenylalanine and leucine, and to a lesser extent at the carboxyl side of glutamic acid residues. It does not cleave at valine, alanine, or glycine linkages. Z-L-tyrosyl-L-phenylalanine, Z-L-glutamyl-L-tyrosine, or Z-L-methionyl-L-tyrosine may be used as substrates for pepsin digestion. Pepsin is inhibited by several phenylalanine-containing peptides.

Why us？

·Passed the Chinese GMP and EU GMP

·27 years of biological enzyme R&D history

·Raw materials are traceable

·Comply with CP、EP、USP and customer standard

·High activity, high purity, high stability

·Export to over 30 countries and regions

·Has the ability of quality system management such as US FDA, Japan PMDA, South Korea MFDS, etc.

Specification

Test Items		Company Specification
Test Items		CP	EP	USP
Characters		White to light yellow powder;	White or slightly yellow,	White or slightly yellow,
		no mildew and deodorant; hygroscopic,	crystalline or amorphous powder	crystalline or amorphous powder
		the aqueous solution shows acidic reaction
Identification		Conforms	Conforms	Conforms
Tests	Loss on drying	≤ 5.0% (Dry environment100℃, 4h)	≤ 5.0% (670Pa 60℃, 4h)	≤ 5.0% (Vacuum decompression 60℃, 4h)
Tests	Residual solvent	————	≤ 5.0%According to EP(5.4)	≤ 5.0%According to USP(467)
Assay		3800~12000U/g	0.5～4.5Ph.Eur.U./mg	3000~20000NF.U/mg
Microbial	TAMC	≤5X10³cfu/g	≤ 10000cfu/g	≤ 10000cfu/g
Impurities	TYMC	≤ 100cfu/g	≤ 100cfu/g	≤ 100cfu/g
	E.coli	Conforms	Conforms	Conforms
	Salmonella	Conforms	Conforms	Conforms

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